General Cell Based Assays
Eurofins Discoverx PathHunter eXpress GPR45 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0374E2ACP1M)
The PathHunter GPR45 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR45 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR45 and EA-tagged β-Arrestin-2. Activation of GPR45 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress SSTR5 U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0402E3CP0L)
The PathHunter SSTR5 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. somatostatin) based activation of SSTR5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR5 and EA-tagged β-Arrestin-2. Activation of SSTR5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR146 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0365E2ACP1L)
The PathHunter GPR146 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR146 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR146 and EA-tagged β-Arrestin-2. Activation of GPR146 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Bioassay Systems EnzyChrom™ a-Amylase Assay Kit. For quantitative determination of a-amylase activity.
For quantitative determination of α-amylase enzyme activity. Key Features: Sensitive and accurate. Linear detection range 0.3 to 50 U/L α-amylase in 96-well plate assay. Convenient. The procedure involves adding a single working reagent, incubation for 15 min, followed by the detection reagent and a 20-min incubation and reading the optical density at 585 nm. Method: OD585nm. Samples: Blood, saliva, urine, agriculture etc. Species: All. Procedure: Assay takes 40 min. Kit size: 100 tests. Detection limit: 0.3 U/L.
Eurofins Discoverx PathHunter eXpress DARC CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0548E2CP1M)
The PathHunter DARC eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of DARC GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged DARC and EA-tagged β-Arrestin-2. Activation of DARC stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human TNF-α / TNFR1 Binding Kit, 500 Assay Points
HTRF Human TNF-α / TNFR1 Binding Kit, 500 Assay Points
Eurofins Discoverx PathHunter eXpress GPR3 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0626E2CP1M)
The PathHunter GPR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR3 and EA-tagged β-Arrestin-2. Activation of GPR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress LGR6 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0527E2ACP1L)
The PathHunter LGR6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of LGR6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged LGR6 and EA-tagged β-Arrestin-2. Activation of LGR6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human Apelin (APJ Receptor) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human Apelin (APJ Receptor) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure AGTRL1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Cell Biolabs Inc Adenosine Assay Kit, 100 assays, Fluorometric, Detection Limit 1.56 μM, 96-well microplate
The Adenosine Assay Kit provides a simple and reliable fluorometric method to quantify total adenosine levels in various biological samples. It is designed for scientific researchers to investigate the roles of adenosine in energy transfer, cell signaling, and blood flow regulation. The kit is optimized for diverse research applications, allowing detection of adenosine levels as low as 1.56 μM, making it suitable for low-abundance samples.
- Accurate quantification of total adenosine in biological samples.
- High sensitivity allows detection of adenosine concentrations as low as 1.56 μM.
- Compatible with cell lysates, tissue lysates, serum, plasma, and urine samples.
- Utilizes a 96-well microplate format for efficient, high-throughput analysis.
- Comprehensive kit includes adenosine standard, assay buffer, fluorometric probe, and necessary enzymes.
Eurofins Discoverx ADP Quest, 8 (800 dp, 384-well). (90-0071)
The ADP Quest kit is a detection kit for the measurement of ADP produced as a product of kinase activity. It is used to detect substrate-induced activity of purified or semi-purified kinases. ADP produced by the kinase reacts with intermediate factors to produce a fluorescent dye precursor, which generates signal when combined with peroxide and peroxidase. The kit is suitable for testing kinetic activity, but can also be run as an end-point assay. This detection kit contains reagents for 2 plates (384-well). For detailed product information, visit www.discoverx.com/products-applications/biochemical-assays.
Eurofins Discoverx PathHunter eXpress GPR148 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0364E2ACP1L)
The PathHunter GPR148 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR148 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR148 and EA-tagged β-Arrestin-2. Activation of GPR148 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
![MOLTOX Molecular Toxicology Inc STDisc TA102 [hisG428,rfa,pKM101,pAQ1], Consists of lyophilized & stablilized S.Typhimurium strain TA97a cells, For use as culture inoculum, 10 discs/vial, Store in Refrigerator](https://assets.fishersci.com/TFS-Assets/CCG/product-images/VN00051761-DISCS.PNG-250.jpg)
MOLTOX Molecular Toxicology Inc STDisc TA102 [hisG428,rfa,pKM101,pAQ1], Consists of lyophilized & stablilized S.Typhimurium strain TA97a cells, For use as culture inoculum, 10 discs/vial, Store in Refrigerator
STDisc™ Salmonella typhimurium strains for use in the bacterial mutagenesis assay described by Maron & Ames, Mutat. Res. 113: 173, 1983. Most commonly employed bacterial strains for use in mutagenicity testing are provided in convenient lyophilized disc format. Strains are periodically characterized and verified for diagnostic performance. Confirmed strains are lyophilized in modified ATCC Reagent 18. After preservation, samples are cultured and their phenotypes and responses to diagnostic mutagens are determined. Strains are accompanied by Quality Control statements that include the results of phenotype confirmation tests, diagnostic mutagen response and viability assessment. Culture instructions are included with the QC Statement. The bacterial strains contained in STDiscs™ and ECDiscs™ are potential etiologic agents and are intended for use only by those skilled in the safe handling of potentially infectious agents.
Eurofins Discoverx AssayComplete Cell Culture Kit-112, (92-3112G)
AssayComplete Cell Culture Kit-112 is an optimized media kit intended for use in culturing and propagating Eurofins DiscoverX cell lines. This kit contains the base medium, relevant serum, and pen/strep required to produce a full cell culture medium for optimal cell culture results. This product is provided as a 3-component kit which will produce approximately 550 mL of finished media. Please refer to cell line specific datasheet to determine the recommended cell culture kit. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter eXpress IL5RA/CSF2RB Dimerization Assay, 10pl Kit. (93-0972E3CP0L)
The PathHunter IL5RA/CSF2RB Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-5) induced dimerization of IL5RA/CSF2RB receptors. This product uses EFC technology. The cell line included overexpresses CSF2RB target protein fused to PK alongside IL5RA target protein fused to EA. Upon ligand-induced dimerization of IL5RA/CSF2RB, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.